Kill or incapacitate an enemy who threw a grenade at you.

Become a mercenary.

Steal the Relic.

Install at least one implant in each system and body part.

Complete a Breach Protocol with a minimum of 3 daemons uploaded.

Find Alt Cunningham.

Interrogate Anders Hellman.

Kill or incapacitate 300 enemies using ranged weapons.

Use a dialogue option related to V's life path 10 times.

Talk with Hanako Arasaka.

Save President Myers.

Kill or incapacitate 3 enemies in quick succession with a revolver or pistol in close combat.

Defeat the Chimera.

Complete Panam Palmer's storyline.

Complete the main storyline.

Reach max Street Cred.

Watch Bushido X with Rogue.

Craft 3 Legendary items.

Complete Judy Alvarez's storyline.

Complete River Ward's storyline.

Complete all Cyberpsycho Sightings.

Kill or incapacitate 50 enemies while time is slowed.

Kill or incapacitate 100 enemies using melee weapons.

Find all the tarot graffiti for the job Fool on the Hill.

Complete “Run This Town”.

Kill or incapacitate 2 enemies with the same sniper rifle shot.

Complete Kerry Eurodyne's storyline.

Steal the Arasaka medical truck or deliver 10 vehicles to El Capitan.

Take Songbird to the stars.

Leave Night City with the Aldecaldos.

Become a legend of the Afterlife.

Complete every Gig in Dogtown.

Collect all items that once belonged to Johnny Silverhand.

Reach the max level in any skill.

Become Dogtown's most wanted criminal.

Buy all vehicles available for purchase.

Eliminate three bosses from the "Increased criminal activity" category.

Refuse Songbird's request.

Take Songbird home.

Perform the Distract Enemies quickhack 30 times without drawing attention to yourself.

Unlock all Perks in the Relic Perk tree.

Let Johnny Silverhand keep your body.

Complete "Things Done Changed".

After reviving with Second Heart, kill or incapacitate the enemy who killed you within 5 seconds.

Complete all gigs and NCPD Scanner Hustles in City Center.

Fulfill Songbird's request.

Complete all gigs and NCPD Scanner Hustles in Heywood.

Complete all gigs and NCPD Scanner Hustles in Westbrook.

Complete all gigs and NCPD Scanner Hustles in the Badlands.

Help Takemura avenge the death of Saburo Arasaka.

Complete all gigs and NCPD Scanner Hustles in Pacifica.

Complete all gigs and NCPD Scanner Hustles in Santo Domingo.

Complete all gigs and NCPD Scanner Hustles in Watson.

Shoot an enemy grenade in midair with a revolver.

Kill or incapacitate 3 enemies with one "Detonate Grenade" quickhack.

Find all fast travel dataterms.

While Berserk cyberware is active, perform a Superhero Landing to kill or incapacitate 2 enemies.